Clinical Laboratory Sciences

School/College: College of Health Sciences

Degree Conferred:

• MS in Clinical Laboratory Sciences

Contents

• Graduate Faculty
• Master of Science in Clinical Laboratory Sciences
• Courses

Overview

The Clinical Laboratory Sciences Program in the Department of Health Sciences offers a program of graduate study providing an advanced level of training for medical technologists and other biomedical scientists. Major emphasis in the program is placed on developing an understanding of the mechanisms of human disease and providing broad-based training in laboratory medicine and biomedical sciences. In-depth training is offered in selected areas of emphasis which include: Biomedical Research in chemistry, hematology, immunology, microbiology, and nutrition; Management; Marketing; and Education. The M.S. degree requirements include a thesis based on research which enhances the student's problem-solving abilities and enables that individual to function more effectively in the clinical laboratory and the biomedical field.

Graduate Faculty

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Professors

Dellinger, John, Ph.D., University of Illinois

Eells, Janis, Ph.D., University of Iowa

Lambrecht, Randall S., Ph.D., University of Wisconsin-Madison

Associate Professors

Azenabor, Anthony, Ph.D., University of Benin, Nigeria

Burlage, Robert, Ph.D., University of Tennessee

Ndon, John, Ph.D., Meharry Medical College

Assistant Professors

Firmani, Marcia, Ph.D., University of California-Berkeley

Lyons, Jeri-Anne, Ph.D., Medical College of Wisconsin

Partington, Susan, Ph.D., University of Wisconsin-Madison

Master of Science in Clinical Laboratory Sciences

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Admission

An applicant must meet Graduate School requirements plus the following requirements to be considered for admission

1. The program primarily enrolls individuals with backgrounds in Clinical Laboratory or a related field who have completed a bachelor's degree at an accredited institution. For students entering without a degree in a related area, the faculty determines deficiencies to be overcome prior to admission. Students may apply for admission at any time during the year; however, review of completed applications will take place twice annually, during the second week of November and March of each year for enrollment beginning the following semester. Applications received after these dates may be considered if space is available in the program. International applicants must have all application materials submitted no less than 8 months prior to the desired date of enrollment. Students may enroll on a full-time or a part-time basis.
2. Applicants may be admitted to regular status if their grade point average is the equivalent of 2.75 or above (scale of 4.0). Averages below 2.75 may be considered for admission on a probationary basis, in which case particular attention is given to the last 60 hours completed in the undergraduate program, with special emphasis on performance in science courses. Probationary status is removed after successful completion of the first eight graduate credits with a grade point average of 3.0 or above.
3. Graduate Record Examination scores on the General Test are required.
4. Three letters of reference, preferably from academic and/or clinical sources, must be submitted.
5. Along with the application form, the applicant must submit a letter of not more than l,000 words stating career objectives and reasons for seeking a graduate degree in clinical laboratory sciences.

Major Professor as Advisor

The student must have a major professor to advise and supervise the student's studies as specified in Graduate School regulations. Students are permitted a choice of research/specialty emphasis, and an advisor is assigned according to faculty advising loads.

Credits and Courses

The minimum degree requirement is 32 graduate credits. A minimum of 6 credits of core curricular requirements must be taken. In addition, a minimum of 4 credits in seminar (710), and a minimum of 8 credits in research (799) must be taken. Of the remaining 14 credits required for the degree, a minimum of 6 credits must be taken as elective subspecialty courses offered by the program.

Thesis

The student must write an acceptable thesis based in part on original research and pass a final oral examination in defense of the thesis.

Time Limit

The student must complete all degree requirements within seven years of initial enrollment.

Courses

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Courses numbered 300-699 are Undergradute/Graduate. Courses numbered 700 and above are Graduate only.

420 Clinical Hematology. 3 cr. U/G.

Lectures in the production, regulation, function, and cytomorphology of normal hematopoietic elements. Introduction to hemostastis theory. Prereq: jr st or cons instr.

427 Clinical Immunology. 3 cr. U/G.

Fundamentals of Clinical Immunology, including cellular, humoral and molecular aspects. Correlation of laboratory test results with clinical disease states. Prereq: jr st.

431 Clinical Chemistry. 3 cr. U/G.

Correlation of clinical chemistry with the pathophysiology of human disease. Prereq: jr st; Chem 501(P) or cons instr; or grad st.

497 Clinical Laboratory Sciences - Study Abroad: (Subtitled). 1-12 cr. U/G.

Designed to enroll students in UWM sponsored program before course work level, content, and credits are determined and/or in specially prepared program course work. Retakable w/chg in topic. Prereq: acceptance to Study Abroad Prog.

534 Medical Microbiology. 2 cr. U/G.

Advanced comprehensive study of microorganisms that influence human health and disease. Emphasis on identification/diagnosis and microbial attributes and mechanisms that facilitate infectious disease. Prereq: jr st & Bio Sci 303(P); or grad st; or cons instr.

535 Medical Microbiology Laboratory. 2 cr. U/G.

Formal systematic laboratory study of microorganisms important in human health and disease. Emphasis on current methods of detection, identification and treatment. 4 hr lab. Prereq: jr st & Bio Sci 303(P), or cons instr; C L Sci 534(C).

537 Medical Parasitology and Mycology. 2 cr. U/G.

Lectures and laboratory dealings with the medically significant parasitic and mycotic agents of human disease. Prereq: sr st in C L Sci Prog; or grad st; or cons instr.

539 Public Health Microbiology. 2 cr. U/G.

The role of microbiological analysis in public health and the current techniques for detecting, identifying, and enumerating pathogenic microorganisms. Prereq: jr st & Bio Sci 383(303)(P), or grad st; or cons instr.

540 Public Health Microbiology Lab. 1 cr. U/G.

Current laboratory techniques for detecting, identifying, and enumerating pathogenic microorganisms. Prereq: jr st, or cons instr; C L Sci 539(C).

552 Advanced Nutrition. 2 cr. U/G.

Nutrient utilization and human metabolism, nutritional influences in anthropology, epidemiology and international development issues. Prereq: jr st; C L Sci 232(P) or Bio Sci 501(P).

555 Toxicology and Therapeutic Drug Monitoring. 1 cr. U/G.

Survey of the pharmacology and analytical methods for identification and quantitation of therapeutic and toxic substances. Prereq: jr st, & Chem 341(P) or 345(P); or cons instr.

560 Molecular Diagnostics. 2 cr. U/G.

Introduction to principles and applications of DNA technology in the clinical laboratory. Prereq: jr st, Chem 501(P); or grad st.

560 (effective 01/26/2009) Molecular and Genetic Diagnostics. 2 cr. U/G.

Introduction to principles and applications of DNA technology in the clinical laboratory. Prereq: jr st, Chem 501(P); or grad st.

561 Molecular Diagnostics Laboratory. 1 cr. U/G.

Clinical laboratory experiences in molecular diagnostic techniques and instrumentation. Prereq: jr st & C L Sci 560(C); or grad st & C L Sci 705(P); or cons instr.

590 Topics in Clinical Laboratory Sciences: (Subtitled). 1-5 cr. U/G.

Topics of current interest in the field of clinical laboratory sciences. The major theme for each semester offering will be posted. May be repeated with change in topic to max of 9 cr for grad students. Prereq: jr st; cons instr for grad cr.

610 Pharmacology. 3 cr. U/G.

Lectures on pharmacokinetics, mechanisms of action, and physiological effects of toxic and therapeutic substances. Prereq: jr st, Chem 501(P), or cons instr.

615 Cellular and Molecular Toxicology. 3 cr. U/G.

Cellular and molecular mechanisms of toxicant interactions with critical target organelles and molecules and subsequent downstream cellular responses. Prereq: jr st, Chem 501(P) or cons instr; or grad st.

620 Forensic Pathology. 2 cr. U/G.

An overview of medicolegal death investigation from the perspective of the forensic pathologist. Prereq: jr st; Bio Sci 203(P).

670 Introduction to Cytometry. 2 cr. U/G.

A basic approach to the science of cytometry including both flow and image analysis. Emphasis on instrumentation and theory. Prereq: jr st, C L Sci 310(P) or equiv, or cons instr.

701 Human Pathophysiology I. 3 cr. G.

An advanced course in basic pathological mechanisms underlying production of human disease and effects on selected organ systems. Prereq: grad st or cons instr.

702 Human Pathophysiology II. 3 cr. G.

A continuation of 701 dealing with pathogenesis of the major diseases of human organ systems. Prereq: grad st; C L Sci 701(P) or cons instr.

705 Molecular Pathology. 3 cr. G.

Principles, methods, and applications of nucleic acid-based technologies in pathology and laboratory medicine. Counts as repeat of C L Sci 590 with similar topic. Prereq: grad st; cons instr.

706 DNA Alterations in Cancer. 3 cr. G.

The molecular basis of cancer; critical evaluation of current literature and clinical utility of various tumor markers. Prereq: grad st.

710 Seminar in Clinical Laboratory Sciences. 1 cr. G.

Presentation of topics of current interest to the clinical laboratory scientist. May be repeated to max of 9 cr. Prereq: grad st or cons instr.

715 Medical Laboratory Management and Education. 2 cr. G.

Introduction to management and education theory and application to the clinical laboratory. Prereq: grad st or cons instr.

717 Laboratory Technology-Theory and Practice. 1 cr. G.

Fundamental laboratory bench techniques common to the biological sciences to prepare students for independent research. Prereq: grad st.

718 Experimental Design, Research, and Epidemiologic Methods. 1 cr. G.

Fundamentals of laboratory, clinical and epidemiologic experimental design for beginning graduate students in the Health Sciences. Prereq: grad st; Biostat or undergrad stats course or cons instr

740 Disorders in Hemostasis. 3 cr. G.

The course is designed to explore the basis for the clinical disorders associated with abnormal hemostasis. Prereq: C L Sci 522, 701 or equiv.

755 Myeloproliferative Syndromes. 3 cr. G.

A comprehensive study of human myeloproliferative disease. Emphasis on cytomorphology of peripheral blood, bone marrow and spleen, cellular markers and lineage regulation. Prereq: grad st; C L Sci 320(P) & 521 or cons instr.

756 Current Concepts in Leukemia. 4 cr. G.

An overview of various forms of human acute and chronic leukemia. Emphasis on cell markers and cytomorphology, clonal etiology and kinetics. Prereq: grad st & cons instr.

762 Clinical Protein Chemistry. 3 cr. G.

Lecture series on the chemistry and physiology of plasma proteins. Case histories, laboratory findings and interpretations of various abnormal disease states are included. Prereq: grad st; cons instr; Chem 501 or equiv.

765 Advanced Physiologic Chemistry. 3 cr. G.

Advanced theoretical skills and an appreciation of the current scientific literature in basic and clinical physiologic chemistry. Prereq: Chem 501(P) or cons instr.

772 Antimicrobial Agents and Chemotherapy. 3 cr. G.

A survey of the effects of antibiotics and chemotherapeutic agents in microorganisms and man. Mode of action, principles of antimicrobial chemotherapy application to basic research. Prereq: lc & la course in medical microbiology; grad st or cons instr.

775 Mechanisms of Infectious Disease. 2 cr. G.

Review of current molecular and cellular aspects of infectious disease as related to microbial determinants of virulence and the host response. Prereq: lc & la course in medical microbiology; grad st or cons instr.

782 Advanced Immunology. 3 cr. G.

Cellular basis of the immune response with emphasis on immunoregulation and clinical disease manifestations resulting from altered cellular immune function. Prereq: grad st; course in immunology; or cons instr.

783 Methods of Clinical Analysis in Immunology. 4 cr. G.

Advanced techniques in the clinical laboratory for detection of humoral and cellular components of the immune response. Prereq: grad st; course in immunology; cons instr.

784 Tumor Biology. 3 cr. G.

Fundamentals of oncology - cell proliferation; biochemistry and epidemiology of cancer; chemical, physical and biological carcinogenesis; host-tumor relationships; diagnosis and therapy. Prereq: grad st or cons instr.

799 Research in Clinical Laboratory Sciences. 1-8 cr. G.

- Prereq: grad st; cons instr.

901 Seminar on Philosophical Approaches to Science. 3 cr. G.

The nature and function of sciences, the logic of the scientific method as it relates to health, and implications of research and practices in health care. C L Sci 901 & LibrlSt 901 are jointly offered; they count as repeats of one another. Prereq: grad st.

909 (effective 01/26/2009) Guided Teaching Experience in Health Sciences. 3 cr. G.

This course provides the student, under the supervision of a faculty member, with the opportunity to design, deliver, and evaluate an undergraduate course. Jointly offered w/ and counts as a repeat of HCA 909. Prereq: grad st; Occ Thpy 900(P); cons instr

910 Advanced Seminar in Health Sciences. 1 cr. G.

Faculty, students, and guests present research topics in the Health Sciences. Retakable to 4 cr max. Prereq: grad st

990 Research and Dissertation. 1-6 cr. G.

Preparation of a dissertation under the direction of the student's primary and secondary advisors. Prereq: grad st; cons instr.

999 Advanced Independent Study. 1-3 cr. G.

Individualized experience enables student to study current topics of interest to the clinical laboratory scientist. Level of credit assigned based on time required for completion. Prereq: grad st; cons instr.